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1

Amyloid blood biomarker detects Alzheimer’s disease prior to clinical onset

Evin, Genevieve

Journal:

Journal of Laboratory and Precision Medicine

Year:

2018

Language:

english

File:

PDF, 161 KB

english, 2018

2

Alzheimer's disease-associated presenilin 1 in neuronal cells: Evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment

Janetta G. Culvenor, Fran Maher, Geneviève Evin, Fiorella Malchiodi-Albedi, Roberto Cappai, John R. Underwood, John B. Davis, Eric H. Karran, Gareth W. Roberts, Konrad Beyreuther, Colin L. Masters

Journal:

Journal of Neuroscience Research

Year:

1997

Language:

english

File:

PDF, 395 KB

english, 1997

3

Increased expression of the amyloid precursor β-secretase in Alzheimer's disease

R. M. Damian Holsinger, Catriona A. McLean, Konrad Beyreuther, Colin L. Masters, Geneviève Evin

Journal:

Annals of Neurology

Year:

2002

Language:

english

File:

PDF, 2.24 MB

english, 2002

4

Increased β-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects

R. M. Damian Holsinger, Catriona A. McLean, Steven J. Collins, Colin L. Masters, Geneviève Evin

Journal:

Annals of Neurology

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

5

Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets

Geneviève Evin, Aiqin Zhu, R.M. Damian Holsinger, Colin L. Masters, Qiao-Xin Li

Journal:

Journal of Neuroscience Research

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

6

Decreased expression of GGA3 Protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein

Claudia Santosa, Stefanie Rasche, Adel Barakat, Shayne A. Bellingham, Michael Ho, Jiangli Tan, Andrew F. Hill, Colin L. Masters, Catriona McLean, Geneviève Evin

Journal:

Neurobiology of Disease

Year:

2011

Language:

english

File:

PDF, 978 KB

english, 2011

7

The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from γ-secretase

Janelle Nunan, Mark S. Shearman, Frédéric Checler, Roberto Cappai, Geneviève Evin, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Year:

2001

Language:

english

File:

PDF, 602 KB

english, 2001

8

Selecting cells with different Alzheimer's disease γ-secretase activity using FACS : Differential effect of presenilin exon 9 deletion on γ- and ε-cleavage

M. Fleur Sernee, Geneviève Evin, Janetta G. Culvenor, José A. Villadangos, Konrad Beyreuther, Colin L. Masters, Roberto Cappai

Journal:

Year:

2003

Language:

english

File:

PDF, 325 KB

english, 2003

9

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

Janetta G. Culvenor, Nancy T. Ilaya, Michael T. Ryan, Louise Canterford, David E. Hoke, Nicholas A. Williamson, Catriona A. McLean, Colin L. Masters, Geneviève Evin

Journal:

Year:

2004

Language:

english

File:

PDF, 358 KB

english, 2004

10

A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease

Victoria M. Perreau, Sandra Orchard, Paul A. Adlard, Shayne A. Bellingham, Roberto Cappai, Giuseppe D. Ciccotosto, Tiffany F. Cowie, Peter J. Crouch, James A. Duce, Genevieve Evin, Noel G. Faux, Andre

Journal:

Year:

2010

Language:

english

File:

PDF, 555 KB

english, 2010

11

A domain level interaction network of amyloid precursor protein and Aβ of Alzheimer's disease

Victoria M. Perreau, Sandra Orchard, Paul A. Adlard, Shayne A. Bellingham, Roberto Cappai, Giuseppe D. Ciccotosto, Tiffany F. Cowie, Peter J. Crouch, James A. Duce, Genevieve Evin, Noel G. Faux, Andre

Journal:

PROTEOMICS - Clinical Applications

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

12

A synthetic substrate assay for the gamma-secretase of the β-A4 amyloid of alzheimer's disease

Dr. Geneviève Evin, Konrad Beyreuther, Colin L. Masters

Journal:

Journal of Peptide Science

Year:

1995

Language:

english

File:

PDF, 600 KB

english, 1995

13

Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle

Nancy T. Ilaya, Geneviève Evin, Colin L. Masters, Janetta G. Culvenor

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 224 KB

english, 2004

14

β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

Jiangli Tan, Geneviève Evin

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 230 KB

english, 2012

15

In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc

David E. Hoke, Jiang-Li Tan, Nancy T. Ilaya, Janetta G. Culvenor, Stephanie J. Smith, Anthony R. White, Colin L. Masters, Geneviève M. Evin

Journal:

Year:

2005

Language:

english

File:

PDF, 479 KB

english, 2005

16

Permafrost research sites in the Alps: Excursions of the international workshop on permafrost and periglacial environments in mountain areas

Wilfried Haeberli, Michèle Evin, Geneviève Tenthorey, H. R. Kensen, Martin Hoelzle, Felix Keller, Daniel Vonder Mühll, Stephan Wagner, Manuela Pelfini, Claudio Smiraglia

Journal:

Permafrost and Periglacial Processes

Year:

1992

Language:

english

File:

PDF, 3.08 MB

english, 1992

17

Presenilin 2 Expression in Neuronal Cells: Induction during Differentiation of Embryonic Carcinoma Cells

Janetta G. Culvenor, Geneviève Evin, Melissa A. Cooney, Hady Wardan, Robyn A. Sharples, Fran Maher, Gullveig Reed, Anke Diehlmann, Andreas Weidemann, Konrad Beyreuther, Colin L. Masters

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 794 KB

english, 2000

18

Gelatinase A possesses a β-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease

Rex N. LePage, Amanda J. Fosang, Stephanie J. Fuller, Gillian Murphy, Geneviève Evin, Konrad Beyreuther, Colin L. Masters, David H. Small

Journal:

Year:

1995

Language:

english

File:

PDF, 456 KB

english, 1995

19

Modulation of amyloid precursor protein processing by synthetic ceramide analogues

Hongyun Li, Woojin S. Kim, Gilles J. Guillemin, Andrew F. Hill, Genevieve Evin, Brett Garner

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

20

BACE: Therapeutic target and potential biomarker for Alzheimer's disease

Geneviève Evin, Adel Barakat, Colin L. Masters

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 356 KB

english, 2010

21

Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex

Margaret J Smith, Robyn A Sharples, Geneviève Evin, Catriona A McLean, Brian Dean, Geoff Pavey, Emmanuelle Fantino, Richard G.H Cotton, Kazunori Imaizumi, Colin L Masters, Roberto Cappai, Janetta G Cu

Journal:

Molecular Brain Research

Year:

2004

Language:

english

File:

PDF, 415 KB

english, 2004

22

APP intracellular domain is increased and soluble Aβ is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease

Amee J George, R.M.Damian Holsinger, Catriona A McLean, Katrina M Laughton, Konrad Beyreuther, Genevieve Evin, Colin L Masters, Qiao-Xin Li

Journal:

Neurobiology of Disease

Year:

2004

Language:

english

File:

PDF, 385 KB

english, 2004

23

Biogenesis and metabolism of Alzheimer’s disease Aβ amyloid peptides

Geneviève Evin, Andreas Weidemann

Journal:

Year:

2002

Language:

english

File:

PDF, 240 KB

english, 2002

24

Subcellular distribution of presenilins, APP and Aβin lymphocytes from a kindred with a new PS1 delta-9 mutation

Genevieve M. Evin, Margaret J. Smith, Robyn A. Sharples, Janetta G. Culvenor

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

25

A new genetic screening assay for gamma-secretase

M. Fleur Sernee, Genevieve M. Evin, Roberto Cappai

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 189 KB

english, 2000

26

O3-03-06: Copper sensitively induces presenilin 1 lipid raft localization with increased amyloidogenic processing of the amyloid precursor protein

Ya Hui Hung, Elysia L. Robb, Irene Volitakis, Genevieve Evin, Katrina M. Laughton, Qiao-Xin Li, Janetta G. Culvenor, Robert Cherny, Ashley I. Bush

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

27

P2-025: Copper depletion by menkes ATP7A over-expression dramatically alters the metabolism of APP and APLP2 in cell culture

Michael A. Cater, Andrew Tsatsanis, Irene Volitakis, Qiao-Xin Li, Genevieve Evin, Julian F.B. Mercer, Colin L. Masters, Robert A. Cherny, Ashley I. Bush

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006

28

Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Cu/Zn-Dependent Superoxide Dismutase Activtity

Mark Greenough, Irene Volitakis, Qiao-Xin Li, Genevieve Evin, Andrew Dalziel, James Camakaris, Ashley Bush

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 58 KB

english, 2011

29

A crossreactive antipeptide monoclonal antibody with specificity for lysyl-lysine

Levon M. Khachigian, Genevieve Evin, Francis J. Morgan, Dwain A. Owensby, Colin N. Chesterman

Journal:

Journal of Immunological Methods

Year:

1991

Language:

english

File:

PDF, 707 KB

english, 1991

30

A crossreactive antipeptide monoclonal antibody with specificity for lysyl-lysine (J. Immunol. Methods 140 (1991) 249–258)

Levon M. Khachigian, Genevieve Evin, Francis J. Morgan, Dwain A. Owensby, Colin N. Chesterman

Journal:

Journal of Immunological Methods

Year:

1992

Language:

english

File:

PDF, 24 KB

english, 1992

31

Levels of [3H]pirenzepine binding in Brodmann's area 6 from subjects with schizophrenia is not associated with changes in the transcription factor SP1 or BACE1

Brian Dean, Andrew Soulby, Geneviève M. Evin, Elizabeth Scarr

Journal:

Schizophrenia Research

Year:

2008

Language:

english

File:

PDF, 442 KB

english, 2008

32

DECREASED NEUREGULIN C-TERMINAL FRAGMENTS IN SCHIZOPHRENIA PREFRONTAL CORTEX BRODMANN'S AREA 6

Adel Barakat, Elizabeth L. Scarr, Brian Dean, Genevieve Evin

Journal:

Schizophrenia Research

Year:

2010

Language:

english

File:

PDF, 88 KB

english, 2010

33

Decreased Neuregulin 1 C-terminal fragment in Brodmann's area 6 of patients with schizophrenia

Adel Barakat, Brian Dean, Elizabeth Scarr, Geneviève Evin

Journal:

Schizophrenia Research

Year:

2010

Language:

english

File:

PDF, 656 KB

english, 2010

34

A substrate analog inhibitor of renin that is effective in vivo

Robert J. Cody, James Burton, Genevieve Evin, Knud Poulsen, J. Alan Herd, Edgar Haber

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 270 KB

english, 1980

35

BACE1 as a Therapeutic Target in Alzheimer’s Disease: Rationale and Current Status

Genevieve Evin, Christopher Hince

Journal:

Year:

2013

Language:

english

File:

PDF, 364 KB

english, 2013

36

P4-256 Nicastrin expression is not coordinated with presenilin level in mouse systemic tissues

Ilaya, Nancy T., Evin, Genevieve, Masters, Colin L., Culvenor, Janetta G.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

37

Decreased expression of GGA1 and GGA3 adaptor proteins in Alzheimer's disease frontal cortex

Evin, Genevieve, Santosa, Claudia, Tan, Jiangli, Barakat, Adel, Masters, Colin L., McLean, Catriona

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

38

P4-292 Gamma-secretase inhibitors stabilize a 900 KDA presenilin complex: a tetrameric model for gamma-secretase

Evin, Genevieve, Canterford, Louise D., Hoke, David E., Holsinger, R.M. Damian, Culvenor, Janetta G., Masters, Colin L.

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 161 KB

english, 2004

39

P3-345: Presenilin-1 interacts with acetylcholinesterase

Saez-Valero, Javier, Silveyra, María-Ximena, Evin, Geneviève, Montenegro, María-Fernanda, Vidal, Cecilo J., Martínez, Salvador, Culvenor, Janetta G.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 71 KB

english, 2008

40

P4-185 Analysis of bace protein and activity in human cerebrospinal fluid

Damian Holsinger, R.M., McLean, Catriona A., Masters, Colin L., Evin, Genevieve

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 162 KB

english, 2004

41

P3-401

Evin, Genevieve, Ho, Michael, Ilaya, Nancy T., Hoke, David E., White, Anthony R., Masters, Colin L., Culvenor, Janetta G.

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

42

P4-206: Identification of gamma-secretase activities with distinct pharmacological properties

Evin, Genevieve, Ho, Michael, Ilaya, Nancy T., Hoke, David E., Laughton, Katrina, Li, Qiao-Xin, Masters, Colin L., Culvenor, Janetta G.

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 66 KB

english, 2008

43

Chemical approach of synthetic immunogens from human renin

Galen, François-X., Evin, Geneviéve, Carelli, Claude, Bouhnik, Jacob, Michel, Jean-B., Ferhentz, Jean-A., Le N'Guyen, Dung, Seyer, René, Carlson, William D., Castro, Bertrand

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1987

Language:

english

File:

PDF, 896 KB

english, 1987

44

The βA4 amyloid protein and its precursors as biological markers for Alzheimer's disease

Masters, Colin L., Bush, Ashley, Evin, Genevieve, Fuller, Stephanie, Li, Quao-Xin, Mackenzie, Ian, Milward, Elizabeth, Moir, Robert, Small, David, Beyreuther, Konrad

Journal:

Neurobiology of Aging

Year:

1990

Language:

english

File:

PDF, 296 KB

english, 1990

45

Processing of the Alzheimer's Disease Amyloid Precursor Protein in Pichia pastoris : Immunodetection of α-, β-, and γ-Secretase Products †

Le Brocque, Darren, Henry, Anna, Cappai, Roberto, Li, Qiao-Xin, Tanner, Jane E., Galatis, Denise, Gray, Carol, Holmes, Steven, Underwood, John R., Beyreuther, Konrad, Masters, Colin L., Evin, Genevièv

Journal:

Year:

1998

Language:

english

File:

PDF, 114 KB

english, 1998

46

A Novel Metalloprotease in Rat Brain Cleaves the Amyloid Precursor Protein of Alzheimer's Disease Generating Amyloidogenic Fragments †

Mok, Su San, Evin, Geneviève, Li, Qiao-Xin, Smith, A. Ian, Beyreuther, Konrad, Masters, Colin L., Small, David H.

Journal:

Year:

1997

Language:

english

File:

PDF, 252 KB

english, 1997

47

Aspartyl Protease Inhibitor Pepstatin Binds to the Presenilins of Alzheimer's Disease †

Evin, Geneviève, Sharples, Robyn A., Weidemann, Andreas, Reinhard, Friedrich B. M., Carbone, Vincenzo, Culvenor, Janetta G., Holsinger, R. M. Damian, Sernee, M. Fleur, Beyreuther, Konrad, Masters, Col

Journal:

Year:

2001

Language:

english

File:

PDF, 168 KB

english, 2001

48

Characterization of five epitopes of human renin from a computer model

Evin, Genevieve, Galen, Francois Xavier, Carlson, William D., Handschumacher, Mark, Novotny, Jiri, Bouhnik, Jacob, Menard, Joel, Corvol, Pierre, Haber, Edgar

Journal:

Year:

1988

Language:

english

File:

PDF, 1.63 MB

english, 1988

49

Candidate .gamma.-Secretases in the Generation of the Carboxyl Terminus of the Alzheimer's Disease .beta.A4 Amyloid: Possible Involvement of Cathepsin D

Evin, Genevieve, Cappai, Roberto, Li, Qiao-Xin, Culvenor, Janetta G., Small, David H., Beyreuther, Konrad, Masters, Colin L.

Journal:

Year:

1995

Language:

english

File:

PDF, 2.79 MB

english, 1995

50

A Novel ɛ-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing †

Weidemann, Andreas, Eggert, Simone, Reinhard, Friedrich B. M., Vogel, Markus, Paliga, Krzysztof, Baier, Gottfried, Masters, Colin L., Beyreuther, Konrad, Evin, Geneviève

Journal:

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002